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The proof

The evidence, graded honestly.

Most sites make claims. We show you the research — what each compound is, what the studies actually found, and where it stands with the FDA. When the evidence is thin, we say so. Every citation links to the primary source so you can check it yourself.

Grade AStrong human evidence

Large randomized trials; FDA-approved for a clear use.

Grade BModerate human evidence

Real human data, often in a narrower population.

Grade CLimited or mixed

Small or conflicting human trials — read closely.

Grade DPreclinical only

No human efficacy trials yet — animal/lab work.

Also in the library

Plain-English overviews for the rest of what we educate on — the compounds and blend formulas beyond the graded set. These are educational, not graded, and not a claim of effectiveness.

More compounds

5-Amino-1MQ

Overview

This is the deeper look behind the short version — what NNMT does and why blocking it was interesting, what the research measured and where they stopped, the oral-capsule question, and what your consultation covers.

Read the overview →

AOD-9604

Overview

This is the deeper look behind the short version — what the pivotal human trial found, why the selectivity claim holds up and the fat-loss claim does not, the bone and liver signals in the laboratory data, and what your consultation covers.

Read the overview →

Ipamorelin

Overview

This is the deeper look behind the short version — how the ghrelin receptor and growth hormone pulse actually work, what the human studies measured, what selectivity does and does not mean, common misunderstandings, who it is not for in full, and what your consultation covers.

Read the overview →

KPV

Overview

This is the deeper look behind the short version — how alpha-MSH signalling works, what the research actually showed, the difference between capsule, injection and cream, common misunderstandings, who it is not for in full, and what your consultation covers.

Read the overview →

Oxytocin

Overview

This is the deeper look behind the short version — how the hospital use and the wellness use differ, what the trust and bonding research actually found, including a major replication failure, and what your consultation covers.

Read the overview →

PE-22-28

Overview

An experimental antidepressant peptide that has been studied only in animals — what the rodent research actually showed, and why 'promising in mice' is a very different claim than 'works in people.'

Read the overview →

Pinealon

Overview

An early-research peptide from the Russian 'bioregulator' tradition — what the laboratory work actually looked at, why almost none of it is human, and what that means for anyone considering it.

Read the overview →

Selank

Overview

This is the deeper look behind the short version — what the Russian anxiety trials actually show, how that evidence compares to FDA-standard trials, common misunderstandings, and what your consultation covers.

Read the overview →

Semax

Overview

This is the deeper look behind the short version — what the Russian stroke-recovery trials actually show, why that is a different claim than cognitive enhancement, common misunderstandings, and what your consultation covers.

Read the overview →

Products are available only by prescription after a consultation with a licensed provider, who decides whether treatment is appropriate. Many compounds described here are not FDA-approved medicines and have not been tested in people for the uses described; information on this site is educational and is not medical advice.